Pharmaceutical industry is the third largest tax paying industry in Bangladesh and contributes almost 1.0% of total GDP. Domestically, pharmaceutical companies produce around 98% of the drugs and only about 2.0%life-saving hi-tech medicines (vaccine, anticancer drug, blood and biosimilar product etc.) that are not produced in the country have been permitted for import. However, most of the ingredients of the domestically produced finished dosage forms are now being imported. Therefore, Pharmaceutical Sciences Research Division is doing research to help pharmaceutical industry overcome the current challenges it faces. Board of BCSIR approved to open the Pharmaceutical Sciences Research Division (PSRD) in BCSIR Laboratories Dhaka in their 216th meeting held on 2nd June, 2011. The main research sections are Drug Discovery and Bioassay, APIs and Pharmaceutical Excipients, Quality Assurance of Modern and Herbal Medicines, Dosage Form Design/Formulation and Biopharmaceutics.
The topics of PSRD research include, but are not limited to:
Chemical exploration and value addition of bioactive molecules from natural sources such medicinal plants and their associated endophytic fungi, Marine plants and their associated symbiotic fungi etc. in view of drug discovery research.
Analytical method development and validation for qualitative and quantitative determination of drugs in bulk and formulation.
Bioanalytical method development and validation for determination of drugs in blood sample.
Bioassay screening of isolated compounds and extracts such as Antioxidant activity, Brine Shrimp Lethality Bioassay, Antimicrobial activity, Cytotoxicity test on cell line.
Synthesis of Active Pharmaceutical Ingredients (APIs).
On-going R&D projects:
Sl.No. Project title Duration
1 Synthesis of some commonly used antiulcerants. July, 2017 – June, 2020
2 Bioassay screening of extracts, fractions and isolated July, 2017 – June, 2020
metabolites obtained from natural sources.
3 Isolation of bioactive metabolites from marine weeds and July, 2016 – June, 2019
sponges as well as their associated symbiotic fungi.
4 Taxonomical identification of symbiotic fungi from medicinal plants. July, 2016 – June, 2019
5 Analytical method development for determination of drugs July, 2016 – June, 2020
in blood samples.
6 Chemical exploration and value addition in bioactive molecules July, 2015 – June, 2020
isolation from medical plants and their associated endophytic fungi.
Analytical Service and HRD:
Human Resource Development:
Patent: Hasan CM, Sohrab MH, Al-Mansur MA: ‘Process for the Preparation of Platelet Boost Capsules from Carica papaya Linn Leaves and the composition thereof’. (Patent No. 1005515, Accepted on 11.05.2014)
Technology: Md. Hossain Sohrab, Satyajit Roy Rony, Sanjida Jahan, Suriya Sharmin, A.D.A. Shahinuzzaman, Mst. Nadira Begum: A process on “Production of Fruit-Flavored Salt for Gastric Comfort’’.
On going: 11 (PhD: 07, MS: 04)
01. Dr. Md. Hossain Sohrab, Principal Scientific Officer & Scientist in Charge
02. Dr. Farhana Afroz, Senior Scientific Officer
03. Satyajit Roy Rony, Scientific Officer
04. A.D. A. Shahinuzzaman, (Study leave) Scientific Officer
05. Suriya Sharmin, Scientific Officer
06. Fatema Moni, Scientific Officer
07. Shammi Akhter, Scientific Officer
Dr. Md. Hossain Sohrab
Pharmaceutical Sciences Research Division, BCSIR Labs, Dhaka
Dr. Qudrat-I-Khuda Road, Dhanmondi, Dhaka 1205.
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